Ibintu hamwe nuburyo:

• Abitabiriye amahugurwa:Igiteranyo cya158 abagabo n'abagore bazima bafite imyaka iri hagatiImyaka 20 na 59bashakishijwe. Abakorerabushake bafite amateka akomeye cyangwa karande yubuvuzi, abarya ibirenzeMl 500 ya kawa, icyayi, ibinyobwa bidasembuye, n'ibinyobwa bisindisha buri munsi, aboyanyweye ibinyobwa bisindisha iminsi irenze ibiri mu cyumweru, abahoze bakoresha inyongera za antioxydeant keraamezi atatu, abanywi b'itabi, abafite imyitozo ikomeye, kandi abatujuje ubuziranenge bwa buri munsi bwa 500 - 2500 ml yamazi meza. Amaherezo, abitabiriye amahugurwa 41 bujuje ibisabwa bahawe amahirwe yo kujya mu itsinda ry’amazi ya hydrogène (n = 22) hamwe n’amazi asanzwe (n = 19). Nyamara, mugihe cyo kwiga, abitabiriye amahugurwa 2 bavuye mu itsinda ry’amazi ya hydrogen na 1 bava mu itsinda ry’amazi asanzwe. Kurangiza,20abitabiriye itsinda ryamazi ya hydrogen na18mumatsinda asanzwe yamazi yarangije igeragezwa ryibyumweru 4.
• Uburyo bwo Gutabara:Itsinda ryamazi ya hydrogène yarariyeLitiro 1.5 y'amazi akungahaye kuri hydrogen(hamwe na hydrogène ya 0,753 ± 0,012 mg / l) buri munsi, mugihe itsinda ryamazi risanzwe ryanyweye amazi angana. Abitabiriye amahugurwa basabwe kurangiza amazi mu icupa rya ml 500 mu isaha imwe nyuma yo kuyifungura. Usibye ikawa, icyayi, ibinyobwa bidasembuye, n'ibinyobwa bisindisha, nta yandi mazi yandi yari yemerewe, kandi kunywa ibyo binyobwa byiyongereye byagenzuwe bitarenze ml 500 ku munsi.

• Ubushobozi bwa Antioxydeant hamwe n’ibyangiritse bya Oxidative: Nyuma yibyumweru bine, kunywa amazi asanzwe hamwe n’amazi akungahaye kuri hydrogène byatumye kwiyongera kwa serumu biologiya anti -xydeant (BAP). Muri rusange, nta tandukaniro rikomeye ryari hagati yitsinda ryamazi ya hydrogène nitsinda risanzwe ryamazi mubijyanye na BAP. Ariko, kubitabiriye barengeje imyaka 30, kunywa amazi ya hydrogène byatumye kwiyongera cyane muri BAP (p = 0.028). Mu itsinda rito (<30 ans), nta ngaruka zikomeye z’amazi ya hydrogène kuri BAP yagaragaye (p = 0.534).
• Apoptose yamaraso ya Periferique Mononuclear selile (PBMCs) hamwe numwirondoro wamaraso yabaturage ba selile Immune:Kuri baseline, nta tandukaniro rikomeye ryagaragaye mu nshuro za selile apoptotique mu maraso hagati yaya matsinda yombi. Ariko, nyuma yikigeragezo cyibyumweru 4, ugereranije nitsinda risanzwe ryamazi, igipimo cya PBMCs apoptotique mumatsinda yamazi ya hydrogen cyari gito cyane (p = 0.036). Byongeye kandi, binyuze mu isesengura rya cytometrie, byagaragaye ko inshuro za selile CD14 + mumatsinda y'amazi ya hydrogène yagabanutse.
• Isesengura ry'inyandiko:Isesengura rya RNA ryakozwe kuri PBMCs ryerekanye ko hari itandukaniro rikomeye hagati yinyandiko mvugo yitsinda rya hydrogène n’itsinda risanzwe ry’amazi. Ikigaragara cyane, imiyoboro yandikirana ijyanye nigisubizo cyo gutwika hamwe ninzira ya NF-κB yerekana inzira mumazi ya hydrogène yagabanijwe cyane.